Chapter 9: Testosterone – Your Secret Strength

178 Testosterone level in the cell and tissue not blood tell us how much testosterone you have: Endocr Rev. 2003 Apr;24(2):152-82 Labrie F et al.; Endocrine Reviews. 2005 May;26(3):322-330. Simpson EL et al.
178 Testosterone in a women’s body is attached to sex hormone binding globulin: Zentralbl Gynakol. 1995;117(10):504-7. Schindler AE.
179 Women’s testosterone expression peaks in early 20s and decreases nearly 50% by mid-forties: Sex Health. 2006 May;3(2):73-8. Burger HG et al.
179 2007 report warned about “substantial, yet-unrecognized” recent decline in men testosterone blood level: J Clin Endo & Metab. Jan;92(1):196-202. Thomas G et al.
181 Animal research shows specific areas of brain directly responding to testosterone: Front Neuroendocrinol. 1996;17(1):51-125. Panzica GC et al.
181 Testosterone has been shown to benefit sexuality of women who haven’t undergone hysterectomy or removal of ovaries:Menopause. 2006 Sep-Oct;13(5):770-9 Shifren JL et al.
181 Women with hysterectomy on estrogen benefit significantly with testosterone treatment:
182 Testosterone significantly reduced women’s fear response:Biol Psychiatry. 2006 May 1;59(9):872-4 Hermans EJ et al.
183 Testosterone supplementation has positive affect on depression: Climacteric. 2004 Dec;7(4):338-46 Studd J et al.
183 Estrogen improves depression and sexual response: J Obstet Gynaecol Res. 2005 Apr;31(2):107-14 Nagata H et al.
184 Addition of testosterone to men who take SSRI(Prozac) improved depression and sexual functions: J Affect Disord. 1998 Mar;48(2-3):157-61 Seidman SN et al.; J Clin Psychiatry. 2005 Nov;66(11):1409-14 Nelson JC et al.
184 Testosterone combined with estrogen and Melatonin alleviates cluster headaches: Headache. 2006 Jun;46(6):925-33 Stillman MJ.
184 Testosterone known as a bone-builder: Gynecol Endocrinol. 2005 Mar;20(3):155-60 Floter A et al.; Clin Endocrinol (Oxf). 2004 Nov;61(5):560-6. Turner A et al.; Maturitas. 2004 Jul 15;48(3):235-42 Tok EC et al.; Br J Obstet Gynaecol. 1992 Sep;99(9):757-60 Savvas M et al.; J Clin Endocrinol Metab. 1996 Jan;81(1):37-43 Raisz LG et al.
184 Testosterone neuroprotective in treatment of MS in men:Arch Neurol. 2007 May;64(5):683-8 Sicotte NL et al
185 Women undergoing IVF enjoy improved results when testosterone is added: Hum Reprod. 2006 Jul;21(7):1884-93 Balasch J et al
185 Testosterone supports follicle function: Hum Reprod. 2006 May;21(5):1204-11 Massin N. et al
185 Decreased testosterone levels associated with increase cardiovascular disease in menopause: Coron Artery Dis. 2007 feb;18(1):9-13 Montalcini T et al.
185 Decreased testosterone in menopause increases thickness of carotid artery wall: J Clin Endocrinol Metab. 1999 Jun;84(6):2008-12 Bernini GP et al.
185 Decreased testosterone associated with increase atherosclerosis: Eur J Endocrinol 2007 Jun;156(6):689-93. Debing E et al.
185 Mice treated with testosterone show improvement in coronary artery function: Fertil Steril. 2006 Oct 31; Cooper BC et al
186 Female-to-male transsexuals do not experience change in mortality: Metabolism. 1989 Sep;38(9):869-73 Asscheman H et al..
186 Testosterone treatment helpful in preventing and treating diabetes: Int J Impot Res. 2006 Jul 20; Svartberg J.
186 Women with polycystic ovaries and testosterone: Fertil Steril, 2006 Mar;85(3):679-88
186 In female-to-male transsexuals large doses of testosterone have no affect on insulin sensitivity: Clin Endocrinol (Oxf). 2003 May;58(5):562-71 Elbers JM et al.
186 Female HIV patients treated with high dose testosterone evidence no change in insulin sensitivity: Fertil Steril. 2006 Jun;85(6):1794-802. Herbst KL et al.
186 Testosterone protects against breast cancer: Endocr Rev. 2003 Apr;24(2):152-82. Labrie F et al.; Cancer Res. 2006 Aug 1;66(15):7775-82. Macedo LF et al.; Menopause. 2007 Mar-Apr;14(2):183-90. Hofling M et al.
186 Testosterone Protects breast cancer by decreasing breast tissue proliferation: Menopause. 2007 Mar-Apri;14(2):183-90 Hoflin M et al.
187 Women to men transexuals have breasts like old postmenopausal women: J Histochem Cytochem. 2006 Aug;54(8):905-10. Stagter MH et al.
187 Historically testosterone was the treatment of choice for breast cancer.
Eur J Surg Oncol. 1987 Apr;13(2):113-7. Karydas I et al.

188 Oral contraceptives decrease close to 80% of the available testosterone: Contraception. 1999 Nov;60(5):255-62. Thorneycroft IH et al.; Acta Derm Venereol. 1984;64(6):517-23. Palatsi R et al.
189 Mortality rates nearly 50% higher in women who remove their ovaries before age 45: Lancet Oncol. 2006 Oct;7(10):821-8. Rocca WA et al.
189 Women lose 70% of testosterone within 72 hours after removal of their ovaries: Maturitas. 2002 Apr 15;41. Rohr UD.
190 Premarin known to increase level of sex-binding globulin:Zentralbl Gynakol. 1995;117(10):504-7. Schindler AE.
190 Women lose sexual drive and function from anti depressive medication and SSRI: NJ Clin Psychiatry. 2001;62 Suppl 3:22-34. Ferguson JM.; Psychother Psychosom. 2006;75(3):187-8. Csoka Ab et al.
190-191 Metyl-testosterone is toxic to liver: N Engl J Med. 1952 Jan 31;246(5):176-9. Brick IB et al.; Ann Intern Med. 1954 Jan;40(1):146-52. Almaden PJ et al.; Bull New Engl Med Cent. 1952 Aug;14(3):87-9. Bonner CD et al.; Am J Med. 1950 Mar;8(3):325-31. Werner SC et al.; Toxicology. 1977 Jun;7(3):357-65. Heywood R. et al.; Bull New Engl Med Cent. 1952 Aug;14(3):87-9. Bonner CD et al.; Gastroenterology. 1956 Oct;31(4):384-90. Kaplan AA.
191 There is no established normal blood level for testosterone in women: Curr Opin Urol. 2002 Nov;12(6):503-7. Anastasiadis AG et al.
191 Many tests yield falsely high results: NAnn Clin Biochem. 2007 Jan;44(Pt 1):5-15. Kane J et al.
191 Because of sloppy testing medical authorities have concluded that it is not possible to make educated assessment about existence of androgen deficiency: J Clin Endocrinol Metab. 2006 Oct;91(10):3697-710. Wierman ME et al.
191 Testosterone expression is determined by levels in cells and tissues (targets): Endocr Rev. 2003 Apr;24(2):152-82. Labrie F et al.
191 Measure of sexual response is not based on blood level: J Sex Med. 2005 May;2(3):291-300. Basson R et al.
191 FDA and various medical associations contend women cannot benefit from testosterone supplementation: J Clin Endocrinol Metab. 2006 Oct;91(10):3697-710. Wierman ME et al.
191 Bioidentical testosterone in pill form decreases women’s level of HDL and fails to yield as good results as other forms:Growth Horm IGF Res. 2006 Jul;16 Suppl A:S109-17. Braunstein GD.; J Clin Endocrinol Metab. 2006 Oct;91(10):3697-710. Wierman ME et al.
191 In US women can get Metyl-testosterone which has found to be toxic to liver: N Engl J Med. 1952 Jan 31;246(5):176-9. Brick IB et al.; Ann Intern Med. 1954 Jan;40(1):146-52. Almaden PJ et al.; Bull New Engl Med Cent. 1952 Aug;14(3):87-9. Bonner CD et al.; Toxicology. 1977 Jun;7(3):357-65. Heywood R et al.; Am J Med. 1950 Mar;8(3):325-31. Werner SC et al.; Gastroenterology. 1956 Oct;31(4):384-90. Kaplan AA.
192 Sublingual testosterone reaches effect in 15 minutes and restores levels within two hours: Arch Gen Psychiatry. 2000 Feb;57(2):149-53. Tuiten A et al.
192 Vaginally applied testosterone cream or gel peaks at 5.5 hours and lasts more than 12: IJ Sex Med. 2006 May;3(3):541-9. Apperloo M et al.
196 Caffeine may counteract loss of head hair and chin hair growth from testosterone: J Sex Med. 2006 May;3(3):541-9. Apperloo M et al.
196 Caution against use of Propecia: Nat Med. 2004 Jul;10(7):704-11. Griffin LD et al.; Semin Cell Dev Biol. 2004 Aug;1594):445-54. Ikonen E et al.

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